Welcome to Prabodh’s Lab

LAB NEWS

  • Sweta Bhambani submitted her thesis.
  • *Congratulations Dr. Smita Kumar and Dr. Ashutosh Pandey for winning the most prestigious Young Scientist Medal-2017 from Indian National Science Academy (INSA).
  • Department of Biotechnology, New Delhi sanctioned Centre of Excellence and Innovation in Biotechnology (CEIB) on Secondary plant product pathway engineering
  • Dr. Smita awarded Indo-Australian Career Boosting Gold Fellowship from DBT to work in Prof. Anthony Miller's group
  • Tapsi Shukla and Aditya V. Agarwal submitted their thesis.
  • 7 publications received Best Research Paper Award-2016 from the Institute.
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    RESEARCH THEMES

    Pathway Engineering for secondary plant products

    In the area of secondary plant metabolites, main focus has been to study the expression and regulation of genes involved in biosynthesis of important molecules, which are beneficial for human health. Lab has attained success in different aspects such as:

  • Transgenic plants accumulate isoflavones. in flower petals, but leaf tissue was devoid of these phytoceuticals.
  • Transformation and development of transgenic plants.
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    Open Position

       There are currently no vacancies available.

     

     

     

     

     

     

     

     

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    Publications

    2015

    1. Gupta P, Goel R, Agarwal AV, Asif MH, Sangwan NS, Sangwan RS, Trivedi PK (2015) Comparative transcriptome analysis of different chemotypes elucidates withanolide biosynthesis pathway from medicinal plant Withania somnifera. Scientific Reports 5:18611 (Nature Publishing Group).

    2. Shukla T, Kumar S, Khare R, Tripathi RD, Trivedi PK (2015) Natural variations in expression of regulatory and detoxification related genes under limiting phosphate and arsenate stress in Arabidopsis thaliana. Frontiers in Plant Science 6:898. doi:10.3389/fpls.2015.00898.

    3. Dixit G, Singh AP, Kumar A, Dwivedi S, Deeba F, Kumar S, Suman S, Adhikari B, Shukla Y, Trivedi PK, Pandey V, Tripathi RD (2015) Sulfur alleviates arsenic toxicity by reducing its accumulation and modulating proteome, amino acids and thiol metabolism in rice leaves. Scientific Reports 5: 16205.

    4. Rai A, Singh R, Shirke PA, Tripathi RD, Trivedi PK, Chakrabarty D (2015) Expression of rice CYP450-like gene (Os08g01480) in Arabidopsis modulates regulatory network leading to heavy metal and other abiotic stress tolerance. PLoS ONE 10:e0138574.

    5. Pandey A, Misra P, Trivedi PK (2015) Constitutive expression of Arabidopsis MYB transcription factor, AtMYB11, in tobacco modulates flavonoid biosynthesis in favour of flavonol accumulation. Plant Cell Reports 34:1515-1528.

    6. Pandey A, Misra P, Choudhary D, Yadav R, Goel R, Bhambhani S, Sanyal I, Trivedi R, Trivedi PK (2015) AtMYB12 expression in tomato leads to large scale differential modulation in transcriptome and flavonoid content in leaf and fruit tissues. Scientific Reports 5:12412 (Nature Publishing Group).

    7. Dixit G, Singh AP, Singh PK, Kumar A, Kumar S, Dwivedi S, Trivedi PK, Pandey V, Tripathi RD (2015) Sulfur mediated reduction of arsenic toxicity involves efficient thiol metabolism and the antioxidant defense system in rice. Journal of Hazardous Materials 298: 241–251.

    8. Pandey V, Dhar YV, Gupta P, Bag SK, Atri N, Asif MH, Trivedi PK, Misra P (2015) Comparative interactions of withanolides and sterols with two members of sterol glycosyltransferases from Withania somnifera. BMC Bioinformatics 16: 120.

    9. Singh AP, Dixit G, Mishra S, Dwivedi S, Tiwari M, Mallick S, Pandey V, Trivedi PK, Chakrabarty D, Tripathi RD (2015) Salicylic acid modulates arsenic toxicity by reducing its root to shoot translocation in rice (Oryza sativa L.). Frontiers in Plant Science 6: 340.

    10. Nair KN, Mishra A, Suseela MR, Trivedi PK, Sawant SV, Nautiyal CS (2015) Transforming plant biology to translational research applications – National Botanical Research Institute. Current Science 108, 1066-1971.

    11. Kumar S, Dubey RS, Tripathi RD, Chakrabarty D, Trivedi PK (2015) Omics and biotechnology of arsenic stress and detoxification in plants: current updates and prospective. Environment International 74, 221-230.

    12. Rai A, Bhardwaj A, Misra P, Bag SK, Adhikari B, Tripathi RD, Trivedi PK, Chakrabarty D (2015) Comparative transcriptional profiling of contrasting genotypes of rice (Oryza sativa L.) in response to arsenic exposure reveals different mechanisms of stress perception and tolerance. Plant Genome-US doi: 10.3835/plantgenome2014.09.0054.

    13. Sharma D, Tiwari M, Lakhwani D, Tripathi RD, Trivedi PK (2015) Differential expression of microRNAs by arsenate and arsenite stress in natural accessions of rice. Metallomics 7, 174-187.

    14. Kumar S, Asif MH, Chakrabarty D, Tripathi RD, Dubey RS, Trivedi PK (2015) Comprehensive analysis of regulatory elements of the promoters of rice sulphate transporter gene family and functional characterisation of OsSul1;1 promoter under different metal stress. Plant Signaling & Behavior 10:4, e990843.

    15. Khedgikar V, Ahmad N, Kushwaha P, Gautam J, Nagar GK, Singh D, Trivedi PK, Mishra PR, Sangwan NS, Trivedi R (2015) Preventive effects of withaferin A isolated from the leaves of an Indian medicinal Plant Withania somnifers (L): comparisons with 17-β-Estradiol and Alendronate. Nutrition 31, 205-213.

     

     

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